[PDF][PDF] Recording EMT activity by lineage tracing during metastasis
P Vieugué, C Blanpain - Developmental cell, 2020 - cell.com
P Vieugué, C Blanpain
Developmental cell, 2020•cell.comIn this issue of Developmental Cell, Li et al. develop a novel lineage tracing system to record
EMT activity during lung metastasis of mammary tumors. Using EMT-tracer mouse models,
they reveal that N-cadherin is transiently expressed by most metastasis-initiating cells and
demonstrate its functional importance during the metastatic cascade.
EMT activity during lung metastasis of mammary tumors. Using EMT-tracer mouse models,
they reveal that N-cadherin is transiently expressed by most metastasis-initiating cells and
demonstrate its functional importance during the metastatic cascade.
In this issue of Developmental Cell, Li et al. develop a novel lineage tracing system to record EMT activity during lung metastasis of mammary tumors. Using EMT-tracer mouse models, they reveal that N-cadherin is transiently expressed by most metastasis-initiating cells and demonstrate its functional importance during the metastatic cascade.
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